Study points to route for ‘one and done’ flu vaccine

pharmaphorum July 22, 2024
Phil Taylor

Scientists in the US have developed a new universal form of influenza vaccine that they say could protect against all strains of the virus – and do away with the annual scramble to match shots to circulating flu strains.

The team led by researchers at Oregon Health & Science University (OHSU) think their ‘one and done’ model – which uses a cytomegalovirus (CMV) vector – could confer lifetime immunity against the evolving virus.

While still in the animal testing stage, initial results published in Nature Communications have been promising against H5N1, a bird flu strain that is a frontrunner to cause a new pandemic.

In the past few years, a highly pathogenic strain of H5N1 has emerged that can jump...

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