Pharmaceutical Executive October 22, 2021
Having proved its efficacy against COVID-19, mRNA technology is positioned to combat another insidious human adversary: cancer.
Cancer is generated by mutations in certain genes, which affect how our cells function. Certain genetic changes arise spontaneously during DNA replication following cell division. Others, on the other hand, are the consequence of DNA damage caused by environmental and occupational factors. Chemicals in cigarette smoke, occupational exposure to asbestos, diesel exhaust, radon, vinyl chloride, benzene, or other carcinogens are examples of these factors.
Because cancer develops from our own cells, the immune system has a far harder time distinguishing proteins in cancer cells as foreign, compared to proteins in pathogens such as viruses. However, significant breakthroughs in cancer biology and genetic sequencing...
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