STAT April 25, 2024
University of Washington professor David Baker has made a name for himself by borrowing computer science concepts like machine learning and artificial intelligence to solve problems in biology. A few years ago, his lab surprised scientists by constructing an AI-powered protein-folding prediction system rivaling Google’s DeepMind AlphaFold. Now Baker is pushing forward in a different area of drug discovery research.
“Look, there’s this huge class of compounds we can make that chemically are just very, very different from proteins,” Baker told STAT, with “building blocks that really don’t look anything like the L-amino...