NEJM July 31, 2024
E. Wesley Ely, M.D., M.P.H. https://orcid.org/0000-0003-3957-2172, Lisa M. Brown, M.P.H., and Harvey V. Fineberg, M.D., Ph.D., for the National Academies of Sciences, Engineering, and Medicine Committee on Examining the Working Definition for Long Covid*

The Covid-19 pandemic has been perceived mainly as a dangerous acute outbreak of infection that killed more than a million people in the United States and 7 million worldwide.1,2 However, in the pandemic’s wake, Covid-19 has left many millions more with a variety of chronic, systemic, and often disabling conditions collectively known as “long Covid.” In the United States alone, survey data indicate that approximately 7% of adults and more than 1% of children — numbering 15 to 20 million Americans and more than 60 million globally — have had long Covid.3,4

Because of the novelty and diverse expression of this condition, a variety of terms and definitions have been advanced for long Covid, although none have gained wide...

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