Blockchain in Healthcare Today December 6, 2025
Fatma M. AbdelSalam, DBA, MBA, FACHDM

Background: Despite blockchain technology’s demonstrated potential to enhance security, transparency, and efficiency in healthcare systems, adoption rates remain significantly lower than predicted, creating a persistent gap between perceived benefits and adoption feasibility. This study addresses the critical question of what explains this adoption paradox by developing and testing a comprehensive theoretical framework that integrates the Technology Acceptance Model (TAM) with the Technology-Organization-Environment (TOE) framework.

Methods: A systematic literature review is conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines to synthesize existing research on blockchain adoption in health care. This study develops four key propositions examining how technology characteristics, organizational factors, external environmental pressures, perceived risks, and system quality collectively influence healthcare organizations’ blockchain adoption intentions.

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