Bio-IT World April 14, 2022
Allison Proffitt

Last month an international team of researchers published whole genome sequencing results comparing thousands of individuals with critical Covid-19 to a control group, discovering and replicating 23 independent variants that significantly predispose an individual to critical Covid-19.

The consortium data came from the GenOMICC study, 23andMe, and the Covid-19 Human Genetics Initiative with additional validation data coming from UK Biobank, AncestryDNA, Penn Medicine Biobank, and Geisinger Health Systems.

“Genomics England did the whole genome sequencing and a genome-wide association study where we tried to associate particular genomic variants in the genome with critical-ness by using the individual cases and participants in another project that we completed a few years ago, the 100,000 Genomes Project,” explained Athanasios Kousathanas, first author on...

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