Medical Xpress December 16, 2025
University of South Australia

Australian scientists have identified the key genetic drivers behind long COVID, revealing why some people continue to experience debilitating symptoms long after their initial infection.

The breakthrough, made using large scale biological datasets, could pave the way for targeted treatments and personalized diagnostics.

The team, led by University of South Australia scientists, integrated genetic and molecular data from more than 100 different international studies, identifying 32 causal genes that increase the likelihood of a person developing long COVID, including 13 new genes not previously associated with the disease.

Their findings have been reported in two new scientific papers published in PLOS Computational Biology and Critical Reviews in Clinical Laboratory Sciences.

An estimated 400 million people have been affected by long...

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