Medscape November 22, 2024
Carolin Hellerich

Nearly every medication comes with side effects, and in cancer therapies, they can be severe. Clinicians must often weigh the benefits of treatment against potential adverse effects. At the 29th Training Week for Practical Dermatology and Venerology in Munich, Germany, specialists explored the manifestations of cutaneous drug reactions and how to manage them.

Immune-Mediated Dermatologic Side Effects

In addition to chemotherapy, there are three other pillars of pharmacologic cancer therapy, as outlined by the first speaker, Mirjana Ziemer, MD, PhD, senior physician and dermatologist at University Hospital Leipzig, Leipzig, Germany:

  • Targeted therapies: Including B-Raf serine-threonine kinase, mitogen-activated protein kinase kinase, Hedgehog, and mammalian target of rapamycin inhibitors.
  • Monoclonal antibodies: Especially immuno-agonistic types.
  • Other immunotherapeutics: Cytokines, chemo-immunoconjugates, oncolytic viruses, and...

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