AI in Healthcare October 26, 2021
Could AI help produce a unifying concept of human disease—one that might help prevent, mitigate or cure everything from birth defects and rare cancers to immune disorders and neurological defects?
Almost certainly not in our lifetimes, argues a distinguished biologist who’s been unraveling cancer genetics and pursuing related avenues of inquiry since the early 1960s.
In 2021 the matter on his mind is AI in service of precision medicine.
“The existence of inherited mutations of various connexin genes [aka ‘gap-junction proteins’] has been associated with specific human disease syndromes as well as with knockout [protein-subtracted] mice models,” writes James Trosko, PhD, in commentary published this month in Diseases.
This association, considered together with “mounting evidence linking specific epigenetic chemicals with...