BioPharma Dive February 6, 2025
Gwendolyn Wu

The biotech, which is testing several experimental cystic fibrosis drugs, is the fourth biotech company to go public in 2025.

Sionna Therapeutics on Thursday raised $191 million in an initial public offering that will fund its plan to challenge Vertex Pharmaceuticals’ dominant cystic fibrosis franchise.

The company sold nearly 10.6 million shares at $18 apiece, more than it projected in a filing earlier this week. It will start trading Friday on the Nasdaq stock exchange under the ticker symbol “SION.”

Sionna is pitching itself as a future threat to Vertex, which since 2012 has brought five cystic fibrosis drugs to market that collectively treat about 90% of people with the condition.

Vertex’s drugs generated about $10 billion in sales in...

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