News-Medical.Net January 20, 2026
A team from the Faculty of Medicine and Health Sciences and the Institute of Neurosciences at the University of Barcelona (UBneuro) has applied advanced artificial intelligence techniques to better understand why Huntington’s disease can begin at very different ages in patients. This hereditary neurodegenerative condition, which causes motor, cognitive, and psychiatric impairments, is caused by a mutation in the HTT gene, which encodes the huntingtin protein.
The mutation in this gene produces a series of CAG repeats that alter the properties and functionality of the huntingtin protein in the brain. Although the length of the CAG repeats in the HTT gene influences the age at which the first symptoms appear, this factor does not fully explain the wide variability observed...
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