News-Medical.Net August 2, 2024
CAR-T cells are highly effective in treating selected blood cancers. However, challenges remain with this new therapy, which was first approved in 2017 in the USA and a year later in Europe for treating acute lymphoblastic leukemia (ALL). For instance, no effective CAR-T cell therapies for solid tumors exist. Furthermore, CAR-T-induced remissions are not always durable, and the production of CAR-T cells is slow and laborious.
Dr. Karl Petri of the University Hospital Würzburg (UKW) / Julius-Maximilians-University Würzburg aims to address these issues using an advanced CRISPR method to increase the efficiency of cancer-directed immunotherapies. The German Research Foundation (DFG) supports his research project with nearly two million euros over the next six years under the Emmy Noether Program.
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