Medical Xpress August 9, 2024
T cell therapies, which use genetically-engineered T cells of the human immune system as therapeutics, are revolutionizing medical oncology by effectively treating previously incurable blood cancers. However, their success against solid tumors has been limited.
How can we make these therapies more effective against a wider range of cancers? Recent studies have shown that stem-like memory T cells, a special type of T cell known for its longevity and ability to proliferate, are key to fighting tumors successfully.
Researchers in the Division of Functional Immune Cell Modulation (LIT), Internal Medicine III (UKR), and the Laboratory of Molecular Immunology, Immunology Center (NHLBI) are developing new methods to enhance the generation of these powerful T cells. Their work is published in the...