HealthsystemCIO.com January 20, 2026
Anthony Guerra

Healthcare organizations deploying AI agents must establish robust guardrails to prevent reputational and clinical harm, even when partnering with leading technology vendors, according to Spencer Dorn, MD, Vice Chair in the Department of Medicine and Lead Informatics Physician at the University of North Carolina at Chapel Hill.

A recent incident at Gap illustrated the stakes involved. The retailer deployed a chatbot developed by a prominent AI company to handle holiday customer service traffic. Despite working with an industry leader, someone maliciously manipulated the chatbot into making offensive statements that generated negative headlines.

“What healthcare CIO wants to wind up on their local news site for the wrong reasons? None of them,” Dorn said. “The stakes are a bit higher in...

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