pharmaphorum January 11, 2024
A major new study in the UK has shown that combining whole-genome sequencing (WGS) and real-world clinical data at a national scale can help deliver tailored, personalised cancer therapy.
The trial – said to be the largest of its kind – drew on the UK’s 100,000 Genomes Project and NHS records and has already led to calls for greater use of genomic testing in cancer care, as it can help select effective therapies for patients and avoid those more likely to cause serious side effects.
Researchers from Genomics England, NHS England, Queen Mary University of London, Guy’s and St Thomas’ NHS Foundation Trust, and the University of Westminster analysed data from more than 30 types of solid tumour in 13,000...