U.S. Overdose Deaths Remain Higher Than in Other Countries — Trend-Tracking and Harm-Reduction Policies Could Help

• The United States has the highest rate of overdose deaths in the world, with more than 100,000 Americans dying by overdose in 2023, according to provisional CDC data

• Compared with other countries, the U.S. approach to reducing overdose deaths is fragmented and inadequate, with policies on interventions such as naloxone and clean syringe services varying widely from state to state

Provisional data show that drug overdoses in the United States claimed more than 100,000 lives for a third consecutive year in 2023 — a more than 50 percent jump since 2019. By a substantial margin, the U.S. has the highest rate of overdose deaths in the world, followed by...

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