Politico November 25, 2025
The second round of Inflation Reduction Act negotiation prices, which includes 15 brand-name drugs, will kick into effect in 2027.
The Trump administration on Tuesday announced $12 billion in federal savings from the second year of Medicare drug price negotiations — a total health officials assert roughly doubles what President Joe Biden secured in the inaugural year of his signature drug pricing law.
The agreed-upon prices will take effect starting in 2027 for 15 drugs, saving people with Medicare prescription drug coverage an estimated $685 million in out-of-pocket costs. The medications were used by about 5.3 million Medicare beneficiaries last year.
They include Pfizer’s breast cancer therapy Ibrance, which was used by 16,000 Medicare Part D beneficiaries in 2024, and...







