Trends in Adverse Event Rates in Hospitalized Patients, 2010-2019

JAMA Network July 12, 2022
Noel Eldridge, MS; Yun Wang, PhD; Mark Metersky, MD; Sheila Eckenrode, MA, RN; Jasie Mathew, MBA; Nancy Sonnenfeld, PhD; Jade Perd ue-Puli, MPA1; David Hunt, MD; P. Jeffrey Brady, MD, MPH1,; Paul McGann, MD; Erin Grace, MHA; David Rodrick, PhD; Elizabeth Drye, MD, SM5; Harlan M. Krumholz, MD, SM

Key Points

Question Were there changes in the rates of in-hospital adverse events between 2010 and 2019?

Findings In this serial cross-sectional study of 244 542 adult patients hospitalized in 3156 US hospitals from 2010 to 2019, there were statistically significant decreases in the annual rates of in-hospital adverse events for admissions for acute myocardial infarction (annual adjusted relative risk [RR], 0.94), heart failure (RR, 0.95), pneumonia (RR, 0.94), major surgical procedures (RR, 0.93), and all other conditions (RR, 0.97).

Meaning The rates of adverse events in hospitalized patients significantly declined for patients with acute myocardial infarction, heart failure, pneumonia, and major surgical procedures between 2010 and 2019 and significantly declined for patients with all other conditions between 2012 and 2019.

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