Medical Xpress September 1, 2022
Scientists have created a roadmap of the genetic mutations present in the most common childhood cancer, acute lymphoblastic leukemia (ALL). The St. Jude Children’s Research Hospital study is the first to supply a comprehensive view of the genomics of all subtypes of ALL. The work serves as a foundational guide for physicians and scientists to understand disease development and improve treatment outcomes. The research was published today in Nature Genetics.
“In this study, we were able to comprehensively define the number and type of recurrently altered genes that are found in childhood ALL,” said co-corresponding author Charles Mullighan, Ph.D., M.B.B.S., St. Jude Department of Pathology. “Because of the scale of the study, we could identify many newly implicated genes that...
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