Advisory Board November 4, 2024

Study details and key findings

TMS is a noninvasive therapy that uses magnetic fields to stimulate the brain, which then causes neurons to fire electrical signals that travel through the brain. Repeated stimulation is believed to help neurons preserve existing connections, while also encouraging them to form new ones.

In 2008, FDA approved TMS to treat depression. Since then, the agency has also approved the therapy to treat migraines, obsessive-compulsive disorder, and to help people quit smoking. Over the last decade, several trials have tested TMS on subjects with Alzheimer’s and have found some signs of efficacy.

In a new Phase 2 trial, Sinaptica tested TMS on 32 patients at the Santa Lucia Foundation, a neurological rehabilitation hospital in Rome....

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