STAT October 7, 2019
Sharon Begley

Two American researchers and one British scientist who independently discovered how cells sense and adapt to oxygen levels won the 2019 Nobel Prize in medicine or physiology on Monday.

Thomas Perlmann, secretary of the Nobel Committee and professor of molecular development biology at the Karolinska Institute, announced the award at a ceremony in Stockholm.

Dr. William Kaelin Jr. of Boston’s Dana-Farber Cancer Institute and Harvard Medical School, Sir Peter Ratcliffe of the University of Oxford and London’s Francis Crick Institute, and Dr. Gregg Semenza of Johns Hopkins University identified “the molecular machinery that regulates the activity of genes in response to varying levels of oxygen, … one of life’s most essential adaptive processes,” the committee said in its announcement. The...

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