MedPage Today August 1, 2024
Nicole Lou

— Exposure may come from food, water, and air

Traces of non-essential and essential metals in urine were associated with increased risk of cardiovascular disease (CVD) and all-cause mortality, according to the largest epidemiological study on the topic to date.

Based on the Multi-Ethnic Study of Atherosclerosis (MESA), individual urinary metals were tied to incident events over more than 17 years when comparing the highest to lowest quartiles:

  • Cadmium: HR 1.25 for CVD (95% CI 1.03-1.53) and HR 1.68 for death (95% CI 1.43-1.96)
  • Tungsten: HR 1.20 for CVD (95% CI 1.01-1.42) and HR 1.16 for death (95% CI 1.01-1.33)
  • Uranium: HR 1.32 for CVD (95% CI 1.08-1.62) and HR 1.32 for death (95% CI 1.12-1.56)
  • Cobalt: HR 1.24...

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