MedPage Today August 1, 2024
— Exposure may come from food, water, and air
Traces of non-essential and essential metals in urine were associated with increased risk of cardiovascular disease (CVD) and all-cause mortality, according to the largest epidemiological study on the topic to date.
Based on the Multi-Ethnic Study of Atherosclerosis (MESA), individual urinary metals were tied to incident events over more than 17 years when comparing the highest to lowest quartiles:
- Cadmium: HR 1.25 for CVD (95% CI 1.03-1.53) and HR 1.68 for death (95% CI 1.43-1.96)
- Tungsten: HR 1.20 for CVD (95% CI 1.01-1.42) and HR 1.16 for death (95% CI 1.01-1.33)
- Uranium: HR 1.32 for CVD (95% CI 1.08-1.62) and HR 1.32 for death (95% CI 1.12-1.56)
- Cobalt: HR 1.24...