Inside Precision Medicine September 26, 2024
The program will create vaccines for various elusive herpesviruses that infect most Americans and cause cancer, autoimmune disease, and birth defects
Erica Ollmann Saphire, PhD, is a structural biologist who studies viral molecular structures to develop frameworks for immune response medicine. As a professor at the La Jolla Institute for Immunology (LJI), Saphire has continued to shed light on the mechanisms by which these glycoproteins function, which is critical for understanding viral entry mechanisms, immunological function suppression, and the sites at which human antibodies can combat these infections.
Saphire’s work has helped to solve the structures of many viral glycoproteins, including those of the Ebola, Sudan, Marburg, Bundibugyo, and Lassa viruses. But one class of viruses—herpesviruses—has long eluded Saphire and,...
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