The Promise and Limits of Remote Patient Monitoring for Bispecific Antibodies

Tara M. Graff, DO, director of clinical research at Mission Cancer + Blood at the University of Iowa Health Care, discussed findings from an abstract at ASH 2025 evaluating the use of remote patient monitoring (RPM) to support outpatient step-up dosing of bispecific antibodies. The analysis explored whether RPM could help a large academic center safely expand outpatient administration and reduce reliance on inpatient hospitalization.

Graff noted that the study, though small, demonstrated potential benefits of RPM, particularly in detecting cytokine release syndrome (CRS) earlier in some patients. Earlier identification of changes in vital signs could allow for more...