HIT Consultant December 23, 2025
Fred Pennic

What You Should Know:

Vyriad, Inc. has secured the final $25M of its Series B financing, bringing the total round to $85M led by Mr. Harry Stine of Stine Seed Farms, Inc.

– The funding will power the first-in-human trials of VV169, an in vivo CAR-T therapy for multiple myeloma that modifies immune cells directly inside the patient’s body. This approach eliminates the complex, expensive lab manufacturing required by current CAR-T treatments, potentially offering a scalable, “off-the-shelf” cure via a single intravenous injection.

The “In Vivo” Revolution: No Lab Required

Current “ex vivo” CAR-T therapies are bespoke and labor-intensive. They require a personalized manufacturing slot for every single patient, leading to bottlenecks that leave desperate patients waiting weeks or...

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