Medscape October 29, 2025
Julie Peck

The rapid rise of GLP-1 receptor agonist prescribing has added another layer of strain on the backs of already overextended primary care clinics. Use of these agents among US adults grew from 0.3% in 2013 to 1.3% in 2023, according to a JAMA Network Open analysis — a dramatic increase that reflects both expanding clinical indications and intensifying patient demand.

For many primary care physicians (PCPs), however, each new prescription sets off a cascade of prior authorizations, data follow-ups, and documentation loops that stretch the limits of clinic capacity and provider workload.

A Mounting Administrative Drag

In a 2024 AMA survey, physicians reported completing an average of 39 prior authorizations per week and spending roughly 13 hours on related...

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