Eric Topol February 22, 2025
U.S. agencies warn health care Industry of new ransomware threat.
B and T lymphocytes contain a treasure chest of information about our immune response to pathogens, vaccination, environmental exposures, and untoward, self-directed attack (to our organs, tissues, and cells). The B and T cell receptors are like antennas, extending outside the cell (Figure below), that act as the sensors to mount a response to these different antigens. Their response is stored, but these receptors are exceedingly complex to decode because their diversity is extreme, with extensive gene rearrangements and somatic mutations. Until now, sequencing these receptors has not been used to diagnose an autoimmune condition or exposure to a pathogen. Their only clinical use case to date has been quite...
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