MedPage Today September 26, 2024
Jennifer Henderson

— Other than staying on drug, there’s no evidence-based strategy to maintain weight loss

This story is part of a series called “Ozempic: Weighing the Risks and Benefits.” It was produced in part through a grant from the NIHCM Foundation.

Looking at the data from clinical trials of new GLP-1 agonists, it’s clear that patients will need to stay on the drugs to maintain their weight loss, experts said.

At the same time, there’s a dearth of evidence as to whether strategies to mitigate weight regain — such as weaning people from the medications — might help, clinicians and researchers told MedPage Today.

“We generally do expect that when folks discontinue this medication they’ll gain at least some weight back,...

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