Becker's Healthcare February 12, 2024
Ashleigh Hollowell

The quantity and risk of fungal infections continues to grow worldwide, particularly as global temperatures warm, creating new environments for fungus to thrive, but drugs to treat these new and emerging infections haven’t kept the same pace.

The last antifungal drug approval was issued by the FDA in 2000. In 2023, a drug known as olorofim was inching closer to FDA approval, but ultimately the agency rejected it, requesting additional data.

Right now, there are only three classes of antifungal drugs, which is few in comparison to antibacterial drugs, of which there are dozens, Leah Cowen, PhD, a professor of molecular genetics at the University of Toronto told NBC News.

Since humans share molecular DNA with fungi, a drug...

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