Eric Topol June 9, 2024

The need for routine assessment and suppression of inflammation

We have known for many years that inflammation is a major driver of atherosclerosis and atherothrombosis (plaque + clot). There are now simple ways to measure body-wide inflammation, coronary artery inflammation, and many ways to reduce inflammation, including lifestyle modifications and inexpensive medications. But none of this has yet been incorporated in routine medical practice. In this issue of Ground Truths, I am going to review the body of evidence for taking inflammation seriously and what ought to amount to a rebooting of our approach to heart and vascular disease.

The Clinical Trials

Yesterday a new randomized trial of colchicine, a potent anti-inflammatory agent, to prevent events after stroke, was published...

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