Medical Xpress August 7, 2024
Chinese Academy of Sciences

Glioblastoma multiforme (GBM) stands as a formidable adversary in oncology, characterized by its molecular complexity and relentless progression. Despite advancements, the high degree of tumor heterogeneity and its tendency to evade conventional therapies pose significant clinical challenges.

The quest for effective treatments is thus propelled by the necessity to unravel the underlying molecular dynamics and the microenvironment’s role in GBM’s resilience.

Researchers from Hebei University, in a collaborative effort, have unveiled a comprehensive review published in the Cancer Biology & Medicine on May 6, 2024, focusing on the molecular subtyping of GBM and the exploration of its mesenchymal transition mechanisms, which are key to developing targeted therapies.

This pioneering research meticulously dissects the genetic mosaic of glioblastoma, spotlighting the...

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