STAT November 30, 2023
Takeda and Janssen are teaming up with wearable device maker ActiGraph to validate a digital measure that quantifies the disruptive nighttime scratching that impacts people with skin conditions like psoriasis and atopic dermatitis. The hope is that a measure of so-called nocturnal scratch might one day be used as an endpoint in clinical trials for new drugs.
Called DECODE, the project will conduct a study enrolling roughly 60 participants with either skin condition who will be filmed with infrared cameras while sleeping with an ActiGraph device worn on each wrist. The video recordings will be used as ground truth for the validation of an algorithm that uses data from the wearable to discern overnight scratching. The study will also collect...
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