News-Medical.Net February 17, 2025
Vlaams Instituut voor Biotechnologie

In a new study published in Science, a Belgian research team explores how genetic switches controlling gene activity define brain cell types across species. They trained deep learning models on human, mouse, and chicken brain data and found that while some cell types are highly conserved between birds and mammals after millions of years of evolution, others have evolved differently. The findings not only shed new light on brain evolution; they also provide powerful tools for studying how gene regulation shapes different cell types, across species or different disease states.

Our brain, and by extension our entire body, is made up of many different types of cells. While they share the same DNA, all these cell types have their own...

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