News-Medical.Net August 29, 2024
In a study that reshapes what we know about COVID-19 and its most perplexing symptoms, scientists have discovered that the blood coagulation protein fibrin causes the unusual clotting and inflammation that have become hallmarks of the disease, while also suppressing the body’s ability to clear the virus.
Importantly, the team also identified a new antibody therapy to combat all of these deleterious effects.
Published in Nature, the study by Gladstone Institutes and collaborators overturns the prevailing theory that blood clotting is merely a consequence of inflammation in COVID-19. Through experiments in the lab and with mice, the researchers show that blood clotting is instead a primary effect, driving other problems-; including toxic inflammation, impaired viral clearance, and neurological symptoms prevalent...
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