Eric Topol September 1, 2024

Multiple new studies and insights

Using high-throughput plasma proteins in large cohorts with extended follow-up, 3 recent organ clock studies that I reviewed highlighted the marked inter-individual and inter-organ variability of the pace of brain aging, its association with mortality, and multiple potential modifiable factors. In recent weeks a cluster of studies have added to our understanding of human brain aging and how it may be influenced. I’ll briefly review the way brain aging is being measured and then get into ways it may be slowed. A recent example below is the impact of HbA1C, an index of glucose regulation, that I’ll get into subsequently.

Measuring Brain Aging

Besides the 3 plasma proteomic studies that tracked the brain clock along...

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