Futurity March 5, 2024
Tracey Peake-NC State

Researchers have developed a new generation of high-performance DNA aptamers and highly accurate drug sensors for cocaine and other drugs.

The sensors are drug specific and can detect trace amounts of fentanyl, heroin, and cocaine—even when these drugs are mixed with other drugs or with cutting agents and adulterants such as caffeine, sugar, or procaine.

The researchers say the sensors could have far-reaching benefits for health care workers and law enforcement agencies.

“This work can provide needed updates to currently used tests, both in health care and law enforcement settings,” says Yi Xiao, associate professor of chemistry at North Carolina State University and corresponding author of two studies describing the work.

“For example, drug field testing currently used by law...

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