Inside Precision Medicine April 17, 2024
Scientists at the Harvard Pilgrim Health Care Institute have made a breakthrough in understanding the development of gestational diabetes (GDM), focusing on the placenta’s role in the condition that affects approximately 14 percent of pregnancies worldwide.
The study, titled “Placental IGFBP1 levels during early pregnancy and the risk of insulin resistance and gestational diabetes,” published in Nature Medicine, examines the relationship between the insulin-like growth factor 1 (IGFBP1) gene in the placenta and its impact on insulin resistance—a key feature of gestational diabetes.
Gestational diabetes not only complicates pregnancy but can also pose long-term health risks for both mother and child, including an increased likelihood of developing type 2 diabetes and cardiovascular diseases. Traditional understanding links excess insulin resistance during...
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