Medical Xpress August 2, 2024
Scientists have developed a new, safe and effective way to infect volunteers with the parasite that causes leishmaniasis and measure the body’s immune response, bringing a vaccine for the neglected tropical disease a step closer.
The breakthrough, by a team from the University of York and Hull York Medical School, lays the foundations for vaccine development and for testing new preventative measures. The article, “Safety and reactogenicity of a controlled human infection model of sand fly-transmitted cutaneous leishmaniasis” is published in the journal Nature Medicine.
Controlled human infection studies, where volunteers are exposed to small amounts of the microbes that cause disease, play a vital role in allowing scientists to provide evidence of the safety and efficacy of new vaccines,...
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