BioPharma Dive September 15, 2025

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The history of diversity in clinical trial populations tells a stark story about medical research in America. Despite decades of regulatory pressure, clinical trials too often exclude some of the very populations they’re meant to serve. Women, members of racial and ethnic minority groups, rural patients, and older adults remain significantly underrepresented in studies that determine whether new drugs and devices work‌ — ‌and for whom.

Under traditional methods, when cancer treatments are studied mainly in urban academic medical centers, the needs of rural patients might never be reflected in‌ life-saving therapies. And when a cardiovascular drug is tested primarily on white men in their 50s, doctors don’t know how it might work for...

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