Medical Xpress September 30, 2025
Jane Kelly, University of Virginia

Huntington’s disease is a fatal, hereditary neurological disorder mostly striking people between the ages of 30 and 50.

In 1872, a young physician, Dr. George Huntington, first described the disease in detail. Since then, a cure has been elusive. That is why word last week that a therapy had been shown to slow the progression of the disease by 75% was breaking news.

Studies show globally, about 1 in 25,000 people have the disease. Dr. Alex Dalrymple runs the University of Virginia’s Huntington’s Disease Program, which the Huntington’s Disease Society of America has designated as a Center of Excellence for 25 years. Dalrymple spoke with UVA Today about the new discovery and why he says there’s room for “cautious optimism.”

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