Fierce Biotech June 3, 2024
Conor Hale

A clinical study found an at-home test based on the DNA found in spit samples could detect cases of prostate cancer that would otherwise slip past a standard blood draw.

Researchers at The Institute of Cancer Research (ICR) in London and The Royal Marsden NHS Foundation Trust discovered a saliva test could help spot the signs of hidden tumors in people whose prostate-specific antigen (PSA) levels fell within normal ranges among men with an already increased genetic risk for the disease.

They also found that when cases were identified, they included a higher proportion of aggressive malignancies versus a PSA blood test. The results of the trial—dubbed BARCODE 1, which studied more than 6,100 men in Europe—were presented at the...

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