AJMC January 3, 2022
Andrew Mulcahy, PhD, MPP, Christine Buttorff, PhD, Kenneth Finegold, PhD, Zeid El-Kilani, MPP, Jon F. Oliver, PhD, Stephen Murphy, PhD, Amber Jessup, PhD

Projected savings from biosimilars from 2021 to 2025 were $38.4 billion vs conditions as of quarter 4 of 2020 and were driven by new biosimilar entry. Savings were $124.5 billion under an upper-bound scenario.

ABSTRACT

Objectives: Biologics account for an increasing share of US prescription drug spending. Biosimilars could lower biologic prices through competition, but barriers to increasing both supply and uptake remain. We projected US biosimilar savings from 2021 to 2025 under different scenarios.

Study Design: We projected US spending on biologics over a 5-year period under 3 scenarios: (1) a baseline scenario holding quarter 4 (Q4) of 2020 market conditions constant; (2) under main assumptions allowing for biosimilar market growth and entry; and (3) an upper-bound scenario assuming...

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