Inside Precision Medicine June 5, 2024
A report published in 2023, estimates that over 40% of adults in the U.S. are obese, defined as a body mass index (BMI) of over 30 kg/m2. While not everyone in this group is unwell, there is no doubt that obesity increases the risk of associated health conditions such as type 2 diabetes, cardiovascular disease, osteoarthritis, sleep apnea, and many others.
The biotech and pharma industry has been trying to develop effective medications to treat obesity for many years. A combined treatment for obesity containing the two appetite suppressants fenfluramine and phentermine (known as fen-phen) was approved and widely used in the early 1990s, but was subsequently withdrawn from the market in 1997 when it became apparent that fenfluramine was...