Becker's Healthcare July 24, 2025
Ella Ruder

The first postpartum depression drug zuranolone, sold under the brand name Zurzuvae, has shown mixed results since its release a year and a half ago, according to a July 22 report in The New York Times. Physicians are navigating the questions of why some women benefit and others do not. About 1 in 8 women experience postpartum depression symptoms, according to the CDC.

Here are five things to note:

  1. Clinical trials found that 60% of women with postpartum depression reported symptom improvement after completing the FDA-approved, 14-day oral medication course.
  1. Some women reported their symptoms “improved remarkably” as early as three days after starting the drug. Most antidepressant medications do not produce results until four to...

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