McKnight’s Senior Living November 29, 2023
(HealthDay News) — Polygenic predisposition to short sleep is associated with depression onset, but polygenic predisposition to depression is not associated with overall sleep duration, short sleep, or long sleep, according to a study published online Oct. 20 in Translational Psychiatry.
Odessa S. Hamilton, from University College London, and colleagues recruited male and female participants aged 50 years and older from the English Longitudinal Study of Ageing to examine the prospective direction involved in suboptimal sleep durations and depression. Summary statistics data from the UK Biobank cohort were used to calculate polygenic scores (PGS) for sleep duration, short sleep and long sleep. At baseline and across an average follow-up of...