Inside Precision Medicine July 25, 2025
Researchers at the University of California, San Diego may now have a clearer understanding of why a particular plant virus effectively activates the immune system to attack cancer cells while other similar viruses do not. The study, published in Cell Biomaterials, details how the cowpea mosaic virus (CPMV) triggers both the innate and adaptive immune pathways, priming the immune system to recognize and fight cancer cells.
“It is fascinating that CPMV, but not other plant viruses, stimulates an anti-tumor response,” said senior author Nicole Steinmetz, PhD, director of nano-ImmunoEngineering at University of California, San Diego.
The new research showed that when CPMV was injected directly into tumors, it triggered a broad immune response drawing neutrophils, macrophages, natural killer cells, and...
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