Medical Xpress October 31, 2024
In a major leap toward more effective cancer treatments, researchers at the University of Oulu have developed an innovative pipeline designed to directly analyze drug responses in primary patient tumor samples.
This method addresses a crucial gap in cancer treatment—the difficulty in identifying the right drug, or combination of drugs, for each patient. The new discovery represents a huge step towards personalized medicine, as it enables the analysis of how individual cancers behave in response to different therapies.
The pipeline, which utilizes live-cell barcoding, enables the simultaneous screening of 96 drug treatments at single-cell resolution.
The study was focused on high-grade serous ovarian cancer (HGSOC), and the pipeline revealed the complex transcriptional landscape of tumors treated with 45 different drugs,...
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