Journal of Clinical Pathways December 18, 2018
Robert W Dubois, MD, PhD

Health care treatments are becoming increasingly tailored to individual patients in terms of patient preferences and individual clinical factors. However, these tailored treatments often have a high price tag. Frameworks or algorithms that are able to assess the value of a specific therapy for a specific patient are needed in order to preserve access to these therapies and better integrate them into the health system from a reimbursement standpoint. Effective value frameworks must incorporate patient preferences, clinical trial subgroup assessments, and post-trial analyses into their design.

The advent of personalized medicine means that therapies are being increasingly tailored to the clinical characteristics and preferences of patients. Obviously, this is a world we all want, where the drugs match who...

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