MedPage Today August 19, 2024
— Adaptive approach senses symptoms before they occur and calibrates stimulation to prevent them
Adaptive deep-brain stimulation (DBS) that used personalized neural signals was feasible and improved motor symptoms in Parkinson’s disease, a cross-over pilot study of four patients showed.
Adaptive DBS reduced the duration of motor symptoms by about 50% relative to conventional DBS, reported Carina Oehrn, MD, PhD, of the University of California San Francisco, and co-authors.
Compared with conventional DBS, Parkinson’s patients with adaptive DBS reported improvement in the percentage of awake time experiencing their most bothersome symptom (β = -16.30%, P<10-3) without worsening the percentage of time with the opposite symptom (β = -2.50%, P=0.26), the researchers wrote in Nature Medicine. The most bothersome symptoms included...
Today's Sponsors
Today's Sponsor