Bio-IT World November 4, 2025
Pacific Biosciences announced a chemistry upgrade and SMRT cell reuse capability last month at the American Society of Human Genetics (ASHG) meeting. CEO Christian Henry said the moves targeted dramatic price reductions for customers and to compete with short-read sequencing.
Henry told Bio-IT World that the launch of the SPRQ-Nx chemistry and SMRT cell reuse capability will bring genome sequencing prices down to $300-$350 per sample—with potential for even lower costs on large-scale projects. Henry described the SPRQ-Nx launch as, “a transformational moment for the company,” marking the culmination of a multi-year effort to “productize this technology from sample extraction through automation through new platforms through informatics.”
The SPRQ-Nx chemistry delivers several improvements...
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